Osthole extracted from a citrus fruit that affects apoptosis on A549 cell line by histone deacetylasese inhibition (HDACs)
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چکیده
منابع مشابه
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line
BACKGROUND Histone deacetylase (HDAC) inhibitors combined with other drugs for the treatment of malignant tumors are used more and more widely. In this study, we investigated the effect of trichostatin A (TSA), a HDAC inhibitor, in combination with cisplatin, a cytotoxic chemotherapy agent, on the apoptosis of lung cancer A549 cells. METHODS A549 cells were treated with TSA alone, cisplatin a...
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ژورنال
عنوان ژورنال: Biotechnology Reports
سال: 2020
ISSN: 2215-017X
DOI: 10.1016/j.btre.2020.e00531